Accommodating the Effect of Ancient DNA Damage on Inferences of Demographic Histories
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منابع مشابه
LETTERS Accommodating the Effect of Ancient DNA Damage on Inferences of Demographic Histories
Andrew Rambaut,* Simon Y.W. Ho,! Alexei J. Drummond," and Beth Shapiro§ *Institute of Evolutionary Biology, University of Edinburgh, King’s Buildings, Edinburgh, United Kingdom; !Centre for Macroevolution and Macroecology, School of Botany and Zoology, Australian National University, Canberra ACT, Australia; "Department of Computer Science, University of Auckland, Auckland, New Zealand; and §De...
متن کاملAccommodating the effect of ancient DNA damage on inferences of demographic histories.
DNA sequences extracted from ancient remains are increasingly used to generate large population data sets, often spanning tens of thousands of years of population history. Bayesian coalescent methods such as those implemented in the software package BEAST can be used to estimate the demographic history of these populations, sometimes resulting in complex scenarios of fluctuations in population ...
متن کاملThe effect of ancient DNA damage on inferences of demographic histories.
The field of ancient DNA (aDNA) is casting new light on many evolutionary questions. However, problems associated with the postmortem instability of DNA may complicate the interpretation of aDNA data. For example, in population genetic studies, the inclusion of damaged DNA may inflate estimates of diversity. In this paper, we examine the effect of DNA damage on population genetic estimates of a...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2008
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/msn256